By Ludmila V. Yakushevich
ISBN-10: 3527404171
ISBN-13: 9783527404179
The 1st version of this booklet used to be the 1st at the physics of DNA to head past the straightforward (simplified) 'linear' process, and it has on the grounds that been chanced on that the inclusion of nonlinear results results in a considerably more desirable interpretation of experimental information. This new version clearly keeps this procedure, yet has been thoroughly revised, up-to-date and accelerated to hide fresh advancements. starting with introductory chapters on DNA constitution and dynamics, the ebook additionally encompasses a comparability among linear and nonlinear techniques to the DNA molecule, a bankruptcy dedicated to the records of nonlinear excitations of DNA, and examples for the translation of experimental information at the dynamics of DNA when it comes to nonlinear thought. crucial analyzing for researchers in biophysics and nonlinear physics, permitting biologists, chemists and physicists to proceed constructing new and more suitable suggestions of investigating the DNA molecule.
Read or Download Nonlinear Physics of DNA PDF
Best bioinformatics books
Read e-book online Information Theory and Evolution PDF
This hugely interdisciplinary ebook discusses the phenomenon of lifestyles, together with its starting place and evolution (and additionally human cultural evolution), opposed to the heritage of thermodynamics, statistical mechanics, and knowledge conception. one of the valuable issues is the seeming contradiction among the second one legislations of thermodynamics and the excessive measure of order and complexity produced by means of residing platforms.
Get Essentials of Genomic and Personalized Medicine PDF
Derived from the great two-volume set, Genomic and customized drugs additionally edited through Drs. Willard and Ginsburg, this paintings serves the wishes of the evolving inhabitants of scientists, researchers, practitioners and scholars which are embracing essentially the most promising avenues for advances in prognosis, prevention and therapy of human ailment.
This publication brings to endure a physique of good judgment synthesis suggestions, to be able to give a contribution to the research and regulate of Boolean Networks (BN) for modeling genetic illnesses similar to melanoma. The authors offer a number of VLSI good judgment recommendations to version the genetic disorder habit as a BN, with strong implicit enumeration suggestions.
This article information modern electroanalytical options of biomolecules and electric phenomena in organic platforms. It provides major advancements in sequence-specific DNA detection for extra effective and good value clinical analysis of genetic and infectious ailments and microbial and viral pathogens.
- Fundamental Concepts of Bioinformatics
- Hydrocarbon and Lipid Microbiology Protocols: Statistics, Data Analysis, Bioinformatics and Modelling
- Applied Genomics of Foodborne Pathogens
- Introduction to Bioinformatics
Extra resources for Nonlinear Physics of DNA
Example text
7). The conformation of the sugar is characterized by four more torsional angles: m0, m1, m2, m3 (which is identical to d), and m4. In addition, one more important structural parameter is the torsional angle of the glycosidic bond, v. The rotational angles of the sugar–phosphate backbone with thymine attached. 2 Possible Motions of the Sugar–Phosphate Backbone When considering the DNA molecule as a dynamical system, we suggest that all parameters described above can be changed. The changes in the values of the torsional angles are in general restricted to the common steric ranges, syn (0 ), anti (180 ), synclinal (–60 ) and anticlinal (–120 ).
It is assumed that the first protein molecule can bind (with good efficiency) to a special range (or site) of the DNA molecule. Let it be called site 1. It is also assumed that the other protein molecule can bind with another site, site 2. Numerous experimental data [203–208] show that the first protein bound at site 1 influences the interaction of the second protein molecule at site 2. The distance between the sites can reach hundreds or thousands of base pairs. This is the reason why the effect is named the long-range effect.
12. 12 (a) One-dimensional lattice (b) with a unit cell (a pair of nucleotides) containing A-T base-pair. For simplicity, the screw symmetry of the model is not shown here. 5. Models of the fifth level of the hierarchy. 13). 13 The most accurate model of the internal DNA structure. 7 Experimental Methods of Studying DNA Structure To study the DNA molecule structure different mathematical, physical, chemical and biochemical methods and combinations of them are used. The history of the discovery of the structure of DNA gives an impressive illustration of this statement.
Nonlinear Physics of DNA by Ludmila V. Yakushevich
by Kevin
4.4