By Rowland H. Davis
ISBN-10: 0195154363
ISBN-13: 9780195154368
ISBN-10: 0195186419
ISBN-13: 9780195186413
Univ. of California, Irvine. presents an historic account of molecular biology, targeting the microorganisms used, how they have been selected, what they contributed, and the way they have been displaced by means of others. Examines the advent of microbial version organisms from 1925 to provide time and explores the increase of genetics and molecular biology. DNLM: Genetics, Microbial--history.
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Additional info for The Microbial Models of Molecular Biology: From Genes to Genomes
Example text
The accomplishments of molecular biology have occasioned misgivings in observers, both within and outside the field. 21 These misgivings are as justified as the regret we feel at an irreversible loss of innocence. Biol ogy is a big science now, much less accessible than in the past to amateurs, and much less widely accessible even to professionals. What we knew 50 years ago is giving way to “systems biology,” the modeling of the workings and integra tion of elements at every level of organization of living things, from metabo lism, cell physiology, development, and organismal physiology to population biology and ecology.
Work on cytology, formal genetics, population genetics, and mutation was proceeding apace, but as a subject for embryology and chemical analysis, Drosophila had to face the hurdle of its small size, its highly differ entiated nature, its exoskeleton, a tough chorion around the embryo, and the possibilities of contamination during microsurgery. The time was ripe for the choice of a still more favorable organism, one that would be chosen not for the pursuit of embryological questions, but instead for the pursuit of biochemical ones.
The time was ripe for the choice of a still more favorable organism, one that would be chosen not for the pursuit of embryological questions, but instead for the pursuit of biochemical ones. As Beadle and Ephrussi’s work unfolded so naturally from the efforts of Morgan and Sturtevant, it brought together genetics and embryology, a longstanding hope of Morgan. The experiments Beadle and Ephrussi performed involved no breeding experiments in which the progeny were analyzed statis tically. 15 The work thus became one of the leading precursors of the field we know as biochemical genetics, using mutations to dissect the course of metabo MORGAN’S PROGENY 23 lism.
The Microbial Models of Molecular Biology: From Genes to Genomes by Rowland H. Davis
by Ronald
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