By Robert G. Forman, Susanna K. Gilmour-White, Nathalie H. Forman
ISBN-10: 052146563X
ISBN-13: 9780521465632
This exact resource of reference offers a accomplished consultant to the hostile side-effects of many regularly prescription drugs on fertility and sexual overall healthiness. greater than one hundred fifty medications are indexed during this compilation, and the facts linking them with infertility and sexual disorder is punctiliously reviewed. the quantity is designed to supply a speedy resource of connection with alert medical professionals and pharmacists to those damaging side-effects. the amount additionally contains an introductory account of the reproductive procedure and a evaluation of the mechanisms during which those medications can intrude or inhibit copy. one other very important topic of the quantity is the influence of social and leisure medications and environmental brokers on reproductive health and wellbeing.
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Sample text
They reduce cardiac output, alter baroreceptor sensitivity and block peripheral p-adrenoceptors. Some p-blockers including propranolol, also reduce renin activity. Propranolol is a non-specific (3^ and P2-receptor-blocking agent. Certain Beta-blockers 23 |3-blockers, notably propranolol, metoprolol and oxprenolol, are lipid soluble. The consequence of this is that these drugs can cross the blood-brain barrier to exert a central nervous system effect. Impotence appears to be the major adverse influence of propranolol on sexual function.
Brennan, W. K. & Bannon, I A. (1990). Efficacy, safety, and quality-of life assessment of captopril antihypertensive therapy in clinical practice. Archives of Internal Medicine, 150,301-6. Smith, P. J. & Talbert, R. L. (1986). Sexual dysfunction with antihypertensives and antipsychotic agents. Clinical Pharmacy, 5, 373-84. Spark, R. F. & Melby, J. C. (1968). Aldosteronism in hypertension. Annals of Internal Medicine, 69, 685-91. Stevenson, J. G. & Umstead, G. S. (1984). Sexual dysfunction due to antihypertensive agents.
McLean and colleagues reported on a small series of patients who developed yawning on treatment. One man and one women experienced orgasm on every or most occasions when they yawned. In the male, this was associated with ejaculation. Another female patient experienced 'irresistible sexual urges' during yawning spells. There is no explanation for this phenomenon (McLean, Forsythe & Kapkin, 1983) Other tricyclic antidepressants Amitriptyline. Decreased libido, several cases of impotence and inhibition of ejaculation have been reported at doses of amitriptyline as low as 50 mg/day.
Drug-Induced Infertility and Sexual Dysfunction by Robert G. Forman, Susanna K. Gilmour-White, Nathalie H. Forman
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