By Mordecai P. Blaustein, Joseph P. Y. Kao, Donald R. Matteson
Achieve a brief and straightforward figuring out of this advanced topic with the second version of mobile body structure and Neurophysiology by means of medical professionals Mordecai P. Blaustein, Joseph PY Kao, and Donald R. Matteson. The multiplied and punctiliously up to date content material during this Mosby body structure Monograph sequence identify bridges the space among easy biochemistry, molecular and phone biology, neuroscience, and organ and structures body structure, delivering the wealthy, clinically orientated insurance you want to grasp the newest techniques in neuroscience. See how cells functionality in well-being and illness with broad dialogue of telephone membranes, motion potentials, membrane proteins/transporters, osmosis, and extra. Intuitive and ordinary, this identify is a powerful technique to research mobile body structure and neurophysiology, and it’s to be had in print and on-line at www.studentconsult.com.
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Extra info for Cellular Physiology and Neurophysiology
63 atmospheres (atm), the osmotic pressure of intracellular and extracellular fluids is quite high, especially in light of the fact that air pressure at sea level is just 1 atm. 63 atm, one needs to dive to a depth of ,67 m (,220 ft) in the ocean. The high osmotic pressure of physiological solutions is the reason that red blood cells, which are much more permeable to water than to solutes, will swell very rapidly and burst (lyse) when they are placed into water or dilute solutions. A note about units of measurement: 1 atm is equivalent to 760 mm of mercury (Hg).
Once again, it is instructive to check the dimensions of the various quantities in Equation . The pressure terms (hydrostatic and osmotic) naturally have units of pressure and can be expressed in units such as atmospheres (atm), millimeters of mercury (mm Hg), or dynes per square centimeter (dyne·cm22). Lp reflects the ability of a certain volume of water to pass through a certain area of membrane, driven by a certain amount of pressure in a certain amount of time, and thus could have units of cm3·cm22·atm21·sec21 (equivalent to cm·atm21·sec21) or cm3·cm22·(dyne·cm22)21·sec21 (equivalent to cm3·dyne21·sec21).
Because an increase in solute concentration dictates a corresponding decrease in water concentration, when a solute concentration gradient exists, a water concentration gradient running in the opposite direction must also be present. We can therefore view simple diffusion as a net flux of solute molecules down their concentration gradient occurring simultaneously with a net flux of water molecules down the water concentration gradient. In the two-compartment situation depicted in Figure 3-1, as osmosis proceeds, the solution volume in 2 will increase and a “head” of solution will build up (Figure 3-1B).
Cellular Physiology and Neurophysiology by Mordecai P. Blaustein, Joseph P. Y. Kao, Donald R. Matteson