Get Protocells: Bridging Nonliving and Living Matter PDF

By Steen Rasmussen;Mark Bedau;Liaohai Chen;David Deamer;David Krakauer;Norman Packard;Peter Stadler

ISBN-10: 0262182688

ISBN-13: 9780262182683

ISBN-10: 1435694090

ISBN-13: 9781435694095

The 1st complete normal source on cutting-edge protocell study, describing present techniques to creating new different types of lifestyles from scratch in the laboratory.

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Extra info for Protocells: Bridging Nonliving and Living Matter

Example text

Such boundary structures, and the compartments they produce, have the potential to make energy available in the form of ion gradients, and can provide a selective inward transport of nutrients. Furthermore, membranous compartments, in principle, are capable of containing unique systems of macromolecules. 2 A protocell would have a minimal set of functional properties, including self-assembly of boundary membranes, transport of monomers, capture of energy to drive polymerization reactions, and encapsulation of polymer systems capable of growth.

There must have been something simpler, a kind of sca¤old-life that was left behind in the evolutionary rubble. Can we reproduce that sca¤old? One possible approach is to incorporate one or a few genes into artificial vesicles to produce molecular systems that display the properties of life. The properties of the system may then provide clues to the process by which life began in a natural setting of the early Earth, and perhaps lead to a second origin of life, but this time in a laboratory setting.

5). These structures were similar in diameter (typically a few microns), with each microsphere containing an estimated 10 10 proteinoid molecules. The proteinoid material formed during the heating step by linking and crosslinking of the amino acid monomers to form more elaborate and complex peptides. These peptides would then interact and self-assemble within minutes into larger macromolecular structures called microspheres (Fox and Dose, 1972). Fox’s microspheres were found to be generally more stable than coacervates.

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Protocells: Bridging Nonliving and Living Matter by Steen Rasmussen;Mark Bedau;Liaohai Chen;David Deamer;David Krakauer;Norman Packard;Peter Stadler


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