Uropathology: A Volume in the High Yield Pathology Series - download pdf or read online

By Ming Zhou MD PhD, George Netto MD, Jonathan I Epstein

ISBN-10: 1437725236

ISBN-13: 9781437725230

Uropathology, a quantity within the High Yield Pathology Series, makes it effortless to recognize the vintage manifestations of urologic ailments and quick be sure your diagnoses. A templated structure, very good colour images, authoritative content material, and on-line entry make Uropathology a terrific reference for busy pathologists.

  • Find info quick and easily with a templated, easy-to-reference layout and concise, bulleted textual content.
  • Confirm your diagnoses with fine quality colour images that display the vintage visual appeal of every affliction.
  • Depend on authoritative information from major specialists within the field.
  • Access the total textual content online, practice speedy searches, and obtain pictures at www.expertconsult.com.

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Extra resources for Uropathology: A Volume in the High Yield Pathology Series

Example text

PAH is basophilic at low power because of a lack of both apical and lateral cytoplasm, whereas most adenocarcinomas of the prostate have more cytoplasm (either eosinophilic or amphophilic) with a paler appearance at low magnification. Sclerosis is not a feature seen with adenocarcinoma. Markedly prominent nucleoli, as seen in some carcinomas, are not present in PAH. Basal cell markers are typically positive in most glands of PAH. Fig 1. Postatrophic hyperplasia; some glands cut tangentially. Fig 2.

Main differential diagnosis • Urothelial carcinoma involving prostate: although immature squamous–urothelial metaplasia in a prostatic infarct may show overt cytologic atypia, recognition of surrounding areas of stromal necrosis and hemorrhage, combined with the histologic zonation typical of infarction (progressively less severe changes away from the center of the lesion), helps to distinguish this benign entity from urothelial carcinoma involving prostatic glands. • Prostatic granulomas secondary to infection: infectious granulomas are often accompanied by grumous cellular debris and epithelioid histiocytes.

The glands are benign and thus also contain basal cells, which are positive for antibodies, such as p63, CK5/6, or high-molecular-weight cytokeratin cocktails. • The stromal component is positive for muscle-specific actin, weakly with S-100, and can also express highmolecular-weight cytokeratin. • Overexpression of AMACR in the glandular component has not been reported. Fig 1. Low-power magnification showing sclerosing adenosis. The lesion lacks the lobular appearance of usual adenosis. A biphasic appearance with glandular and myxoid areas is visible.

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Uropathology: A Volume in the High Yield Pathology Series by Ming Zhou MD PhD, George Netto MD, Jonathan I Epstein


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