By Ronald A Asherson
ISBN-10: 0080527302
ISBN-13: 9780080527307
ISBN-10: 0444509879
ISBN-13: 9780444509871
ISBN-10: 1435610229
ISBN-13: 9781435610224
This booklet offers the reader with a finished evaluate of the Antiphospholipid syndrome. some of the most very important advances in rheumatology and connective tissue ailments of the decade. It presents a proof for lots of formerly undefined stipulations without transparent pathogenesis encompassing all subspeculations in inner medication in addition to obstetrics. Clotting difficulties resulting in strokes and myocardial Read more...
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Extra info for The antiphospholipid syndrome II: autoimmune thrombosis
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1995; 73(3): 444-452. Tincani A, Allegri F, Sanmarco M, Cinquini M, Taglietti M, Balestrieri G, Koike T, Ichikawa K, Meroni P, Boffa MC. Anticardiolipin antibody assay: a methodolgical analysis for a better consensus in routine determinations ~ a cooperative project of the European Antiphospholiid Forum. Thromb Haemost 2001; 86(2): 575-583. Pierangeh SS, Liu X, Barker JH, Anderson GH. Harris EN. Induction of thrombosis in a mouse model of IgG, IgM and IgA immunoglobulins from patients with Antiphospholipid Syndrome.
Pediatr Hematol Oncol 1993;10:311-315. Hellan M, Kuhnel E, Speiser W, Lechner K, Eichinger S. Familial lupus anticoagulant: a case report and review of the literature. Blood Coagul Fibrinolysis. 1998;9:195-200. Oosting JD, Derksen RH, Entjes HT, Bouma BN, de Groot PG. Lupus anticoagulant activity is frequently dependent on the presence of beta 2-glycoprotein-I Thromb Haemost 1992;67:499-502. Roubey RA, Pratt CW, Buy on JP, Winfield JB. Lupus anticoagulant activity of autoimmune antiphospholipid antibodies is dependent upon beta 2-glycoprotein I.
The proposed algorithm indicates that in the initial stages, the aCL and LA tests should be performed as a first line of testing. If any of these tests are negative or both, then a more specific test should be performed such as the B^GPI or the APhL® ELISA Kit. Based on the sensitivity and specificity data accumulated thus far, we propose that the APhL®ELISA kit may be used initially instead of the aCL ELISA. Finally, there have been increasing number of reports from some various centers suggesting that patients with APS have antibodies that bind proteins other than B^GPl in recently (discussed more in detail in previous sections) developed ELISA tests.
The antiphospholipid syndrome II: autoimmune thrombosis by Ronald A Asherson
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