By Donnenberg
ISBN-10: 0122207513
ISBN-13: 9780122207518
Escherichia coli: Virulence Mechanisms of a flexible Pathogen is a different, complete research of the biology and molecular mechanisms that let this ubiquitous organism to thrive. best investigators within the box speak about the molecular foundation of E. coli pathogenesis by means of chapters on genomics and evolution. distinct descriptions of unique traces demonstrate the molecular pathogenesis of every and the explanations of intestinal and extra-intestinal infections in people. Escherichia coli: Virulence Mechanisms of a flexible Pathogen concludes with a presentation of virulence components, universal to 2 or extra pathotypes. This certain assortment offers well timed and important info on figuring out the interior workings of E. coli, in order to lend key insights into ailment prevention study. Key positive factors* unmarried resource of data of E. coli pathogenesis* specialist authors* accomplished insurance* Molecular mechanisms* Biology, evolution and genomics* fresh advances
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157:690-693. 35. Cairns, J. (1963). The chromosome of Escherichia coli. Cold Spring Harbor Symp. Quant. Biol. 28:43-46. 36. Pettijohn, D. E. (1996). The nucleoid. In Escherichia coli and Salmonella: Cellular and Molecular Biology (E C. Neidhardt, R . Curtis, III, J. L. ),VoL 1, pp. 158-166. ASM Press, Washington. 37. , and Broda, P. (1971). Evidence for the bidirectional rephcation of the Escherichia coli chromosome. Nature New Biol. 232:137-140. 38. , Pelletier, A. , and Hill, T. M. (1989). Tus and the terminators: The arrest of rephcation in prokaryotes.
Coli Genomes 23 TABLE II (Continued) OI# Size (bp) Description 1 6,506 166 6,318 Putative PTS for sorbose, R E P region 95 6,185 Aromatic degradation cluster, LysR-type regulator, partial BoxC repeat 9 6,133 Unknov^ns including three O R F s similar to cluster implicated in regulation of a /? aeruginosa porin for imipenem/basic amino acid uptake, begins within B02S2-YagP, putative regulator 144 6,091 Unknowns, putative adhesin 141 5,904 Putative fimbrial subunits, usher and chaperone 173 5,646 Putative invasin, putative transport protein, unknowns, R E P region 162 5,521 Rhs core, unknowns, part of IS element 145 5,407 Putative LPS biosynthesis enzymes 14 5,279 Unknowns 17 5,258 Putative sugar (possibly ribose) transport system 90 5,131 Putative regulator of molybdate metabolism Putative type I fimbrial protein, usher and chaperone, unknowns pathogenic functions.
L. E. coli Genomes 57. 58. 59. 60. 61. 62. 63. 64. 65. 66. 67. 68. 69. 70. 71. 72. 73. 74. 75. 76. 77. 47 Ingraham, K. B. ),Vol. 2, pp. 1649-1654. American Society for Microbiology, Washington. , et al. (1990). Deletions of chromosomal regions coding for fimbriae and hemolysins occur in vitro and in vivo in various extraintestinal Escherichia coli isolates. Microh. Pathog. 8:213-225. , and Kaper,J. B. (2000). Pathogenicity islands and the evolution of microbes. Annu. Rev. Microbiol. 54:641-679.
Pathogenic E. coli : paradigm for bacterial pathogenesis by Donnenberg
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