By Robert J. Gillies
ISBN-10: 0122839803
ISBN-13: 9780122839801
This booklet offers a entire assessment of contemporary nuclear magnetic resonance ways to biomedical difficulties in vivo utilizing state of the art thoughts. It devotes equivalent awareness to the tools and purposes of NMR and addresses the possibility of all the options mentioned. the amount comprises late-breaking parts resembling sensible imaging, circulate imaging, bioreactor spectroscopy, and chemical shift imaging. All chapters are written in a ''current concepts'' variety that renders info obtainable to readers in any respect degrees. individuals are identified specialists within the box, lending the e-book a world viewpoint
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Additional info for NMR in Physiology and Biomedicine
Sample text
L. (1953). Free nuclear induction. Phys. Today 6 (11), 4 - 9 . Harris, R. K. (1983). " Pitman, London. Hoult, D. L, and Richards, R. E. (1976). The signal-to-noise ratio of the nuclear magnetic resonance experiment. / . Magn. Reson. 2 4 , 71-85. / • Introduction to NMR Jeneer, J . (1971). NMR excitation with two pulses. Ampere Interna tional Summer School, Basko Polje, Yugoslavia. , and Tomita, K. (1954). A general theory of magnetic reso nance absorption. / . Phys. Soc. Jpn. 9, 8 8 8 - 9 1 9 .
A large number of atomic nuclei are detectable by M R , and any mole cule which contains an MR-detectable nucleus and can be injected into a living organism in detectable concen trations can be used as a tracer molecule. D above) can be followed based on the effect of the con trast agent on M R proton image intensity. A number of tracer methods which have been used successfully are discussed below. A. Deuterium Oxide The deuterium nucleus is M R detectable and thus deuterated water is an excellent tracer molecule for mea surement of blood flow (See Chap.
The precession frequency is deter mined by the strength of the nuclear magnetic moment (or the gyromagnetic ratio; γ) and the strength of the applied field (B), and is given by the Larmor equation ω = γΒ. I. T H E NUCLEAR M A G N E T I C RESONANCE SIGNAL Fundamental principles of magnetic resonance (MR) are discussed in detail in Chapter 1. Some impor tant concepts are summarized here to facilitate presenta tion of imaging methods. A. Polarization of Atomic Nuclei Magnetic resonance (frequently referred to as nu clear magnetic resonance) signals are detected from atomic nuclei which possess angular momentum.
NMR in Physiology and Biomedicine by Robert J. Gillies
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