New PDF release: Nephron-Sparing Surgery

By Krishna Sasidharan, Mark Soloway

ISBN-10: 1841846368

ISBN-13: 9781841846361

In August 2005, Dr. Michael Blute on the Mayo health center said that open nephron-sparing surgical procedure is still the 'gold usual' for open surgical procedure for kidney tumors and may stay the 1st selection for plenty of sufferers. This demanding situations the concept less-invasive treatments are consistently stronger than open surgical procedure. whereas laparoscopic nephron-sparing surgical procedure is possible for small, simply obtainable kidney tumors; for giant tumors this isn't consistently the case. Drs. Sasidharan and Soloway have created an outstanding textual content masking all features of nephron-sparing surgical procedure and supply very good assistance for all those people who are simply commencing to practice NSS or act as an reduction for these accustomed to NSS.

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Cheville JC, Lohse CM, Zincke H et al. Comparisons of outcome and prognostic features among histologic subtypes of renal cell carcinoma. Am J Surg Pathol 2003; 27(5): 612–24. 20. Kovacs G, Fuzesi L, Emanuel A et al. Cytogenetics of papillary renal cell tumors. Genes Chromosomes Cancer 1991; 3(4): 249–55. 21. Schmidt L, Duh FM, Chen F et al. Germline and somatic mutations in the tyrosine kinase domain of the MET protooncogene in papillary renal carcinomas. Nat Genet 1997; 16(1): 68–73. 22. Delahunt B, Eble JN.

6 Papillary renal cell carcinoma type 1. (A) Low-power image showing numerous papillary structures. (B) Higher-power image of the papillae with fibrovascular cores focally containing foamy histiocytes. 7 Papillary renal cell carcinoma with a homogeneous yellow/tan color. 17,24 This tumor accounts for about 5% of RCC and has equal sex distribution. 26 The Birt–Hogg–Dubé syndrome is a rare autosomal dominant disorder characterized by hair follicle hamartomas (fibrofolliculomas) of the face and neck.

10). 14,30 It carries a poor prognosis as the stage is often advanced at the time of diagnosis. 31 Grossly, the tumor cut surface is gray-white. It has indistinct borders, an epicenter in the medulla, central necrosis, and it often invades into the perirenal tissues. 11). 30 The stroma commonly appears with a prominent desmoplastic and inflammatory response around the tumor. The immunophenotype has been expanded in the 2004 WHO classification:14 it is positive for keratins of low (LMW) and high molecular weight (HMW) and vimentin, but molecular alterations are poorly understood.

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Nephron-Sparing Surgery by Krishna Sasidharan, Mark Soloway


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