Download PDF by J Fred Dice: Lysosomal Pathways of Protein Degradation

By J Fred Dice

ISBN-10: 1587060035

ISBN-13: 9781587060038

Within the mobile there are significant pathways of proteolysis: the lysosomal pathway and the ubiquitin/proteasome pathway. This e-book describes mechanisms of protein degradation through lysosomal pathways.

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Ubiquitin Lys63 is involved in ubiquitination of a yeast plasma membrane protein. EMBO J 1997; 16:5847-5854. 20. Springael J-Y, André B. Nitrogen-regulated ubiquitination of the Gap1 permease of Saccharomyces cerevisiae. Mol Biol Cell 1998; 9:1253-1263. 21. Cenciarelli C, Hou D, Hsu K-C et al. Activation-induced ubiquitination of the T-cell antigen receptor. Science 1992; 257:795-797. 22. Mori S, Heldin CH, Claesson-Welsh L. Ligand-induced polyubiquitination of the platelet-derived growth factor β-receptor.

Science 1996; 273:1725-1728. 114. Plemper RK, Böhmler S, Bordallo J et al. Mutant analysis links the translocon and BIP to retrograde protein transport for ER degradation. Nature 1997; 388:891-895. 115. Strous GJ, van Kerkhof P, Govers R et al. The ubiquitin conjugation system is required for ligandinduced endocytosis and degradation of the growth hormone receptor. EMBO J 1996; 14:3806-3812. 116. Hicke L, Zanolari B, Riezman H. Cytoplasmic tail phosphorylation of the α factor receptor is required for its ubiquitination and internalization.

A single mutation in Chinese hamster ovary cells impairs both Golgi and endosomal function. J Cell Biol 1984; 99:1296-1308. 61. White JM. Membrane fusion. Science 1992; 258:917-923. 62. Janin J, Chothia C. The structure of protein-protein recognition sites. J Biol Chem 1990; 265:16027-16030. 63. Stepp JD, Huang L, Lemmon SK. The yeast adaptor protein complex, AP-3, is essential for the efficient delivery of alkaline phosphatase to the vacuole. J Cell Biol 1997; 139:1761-1774. 64. Odorizzi G, Cowles CR, Emr SD.

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Lysosomal Pathways of Protein Degradation by J Fred Dice


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