Arthur M. Lesk's Database Annotation in Molecular Biology: Principles and PDF

By Arthur M. Lesk

ISBN-10: 0470856815

ISBN-13: 9780470856819

ISBN-10: 0470856858

ISBN-13: 9780470856857

Components dominate present molecular biology: the quantity of uncooked facts is expanding very swiftly and profitable functions in biomedical study require conscientiously curated and annotated databases. the standard of the experimental facts -- specifically nucleic acid sequences -- is passable; even though, annotations rely on gains inferred from the knowledge instead of measured without delay, for example the identity of genes in genome sequences. it truly is crucial that those inferences are as exact as attainable and this calls for human intervention.With the popularity of the significance of exact database annotation and the requirement for people with specific constellations of abilities to hold it out, annotators are rising as experts in the occupation of bioinformatics. This booklet compiles information regarding annotation -- its present prestige, what's required to enhance it, what talents needs to be delivered to endure on database curation and therefore what's the right education for annotators.The publication might be crucial interpreting for everyone engaged on organic databases, either biologists and computing device scientists. it's going to even be of curiosity to all clients of such databases, together with molecular biologists, geneticists, protein chemists, clinicians and drug builders.

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A. and Barrell, B. (2000). Artemis: sequence visualization and annotation. Bioinformatics 16 (10), 944–945. D. and Birney, E. (2002). The BioPerl toolkit: Perl modules for the life sciences. Genome Res. 12, 1611–1618. Stein, L. (2001). Genome Annotation: from sequence to biology. Nat. Rev. Genet. 2, 493–503. , Arva, A. and Lewis, S. (2002). The Generic Genome Browser: a building block for a model organism database. Genome Res. 12 (10), 1599–1610. D. and Thierry-Mieg, J. (1998). Scriptable access to the Caenorhabditis elegans genome sequence and other AceDB databases.

Nucleic Acids Res. 31, 365– 370. , Matise, T. and Preuss D. (2002). Nucleotide sequence database policies. Science 298, 1333. O. (1976). The origin and evolution of protein superfamilies. Fed. Proc. 35, 2132– 2138. , Gateau, A. and Apweiler, R. (1999). A novel method for automatic and reliable functional annotation. Bioinformatics 15, 228–233. FlyBase Consortium. (2003). The FlyBase database of the Drosophila genome projects and community literature. Nucleic Acids Res. 31, 172–175. , Jung, E. and Bairoch, A.

2003). The Swiss-Prot protein knowledgebase and its supplement trembl in 2003. Nucleic Acids Res. 31, 365–370. Bork. , Huynen, M. and Yuan, Y. (1998). Predicting Function: from genes to genomes and back. J. Mol. Biol. 283, 707–725. S. S. (1985). The GenBank nucleic acid sequence database. Comput. Appl. Biosci. 1 (4), 225–233. , Gouzy, J. and Kahn, D. (2000). Prodom and Prodom-CG: Tools for protein domain analysis and whole genome comparisons. Nucleic Acids Res. 28(1), 267–269. R. and Stein, L.

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Database Annotation in Molecular Biology: Principles and Practice by Arthur M. Lesk

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