Read e-book online Cortical Deficits in Schizophrenia: From Genes to Function PDF

By Patricio (Ed.) O'Donnell, Patricio O'Donnell

ISBN-10: 0387743502

ISBN-13: 9780387743509

This highly vital textual content goals to light up the most tough components of analysis in psychiatric medication – the foundation for schizophrenia in human DNA. The genetics of schizophrenia were elusive for many years. in recent times, despite the fact that, a posh set of genes and gene adaptations that confer predisposition to schizophrenia were pointed out. The problem is to appreciate the biology of the genes and learn how they exert their impression. this is the entire most up-to-date examine.

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Hennah W, Tuulio-Henriksson A, Paunio T (2005) A haplotype within the DISC1 gene is associated with visual memory functions in families with a high density of schizophrenia. Mol Psychiatry 10:1097-1103. Hodgkinson CA, Goldman D, Jaeger J, Persaud S, Kane JM, Lipsky RH, Malhotra AK (2004) Disrupted in schizophrenia 1 (DISC1): Association with schizophrenia, schizoaffective disorder, and bipolar disorder. Am. J. Hum. Genet 75:862-872. DISC-1 and Dysbindin Effects on Cognitive Function 27 Jacobsen LK, Giedd JN, Castellanos FX, Vaituzis AC, Hamburger SD, Kumra S, et al.

Keverne EB (1999) GABA-ergic Neurons and the Neurobiology of Schizophrenia and other Psychoses. Brain Res Bull 48:467-473. Kendler KS, Karkowski-Shuman L, O'Neill FA, Straub RE, MacLean CJ, Walsh D (1997) Resemblance of psychotic symptoms and syndromes in affected sibling pairs from the Irish Study of High-Density Schizophrenia Families: evidence for possible etiologic heterogeneity. Am J Psychiatry 154:191-198. Kendler KS (2004) Schizophrenia genetics and dysbindin: a corner turned? Am J Psychiatry 161:1533-1536.

Sawamura N, Sawamura-Yamamoto T, Ozeki Y, Ross CA, Sawa A (2005) A form of DISC1 enriched in nucleus: altered subcellular distribution in orbitofrontal cortex in psychosis and substance/alcohol abuse. Proc Natl Acad Sci USA 102:1187-1192. 28 Anil K. Malhotra et al. St Clair D, Blackwood D, Muir W, Carothers A, Walker M, Spowart G, Gosden C, Evans HJ (1990) Association within a family of a balanced autosomal translocation with major mental illness. Lancet 336:13-16. Strasser HC, Lilyestrom J, Ashby ER, Honeycutt NA, Schretlen DJ, Pulver AE, et al.

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Cortical Deficits in Schizophrenia: From Genes to Function by Patricio (Ed.) O'Donnell, Patricio O'Donnell

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