By Jose Feola (auth.), Jacek G. Wierzbicki (eds.)
Californium-252 is a neutron emitter with a excessive particular task, making it invaluable in a number of purposes, the main stunning of that is in brachytherapy for melanoma sufferers. Radiation oncology has exhausted approximately each alternative for treating radioresistant tumors by way of photon brachytherapy, and as a result new kinds of radiation must be studied to enhance the curability of melanoma.
Audience: Californium brachytherapy is utilized in just a couple of radiation remedy facilities on the planet, so the ebook may be hugely instructive for radiation oncologists, scientific physicists and radiobiologists. The nuclear ideas utilized in medical purposes can also curiosity nuclear physicists and engineers.
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Extra info for Californium-252 Isotope for 21st Century Radiotherapy
4. Browne, E. and Firestone, R. B. (1986) in V. S. ), Table o/Radioactive Isotopes, Wiley-Interscience, New York, pp. 249-1 - 254-1. 5. Axton, N. E. (1986/87) Intercomparison of neutron-source emission rates (19791984), Metrologia 23, 129-144. 6. Grundl,1. and Eisenhauer, C. (1975) Fission rate measurements for materials neutron dosimetry in reactor environments, in Proceedings o/the First ASTM-EURATOM Symposium on Reactor Dosimetry, pp. 425-454. 7. Holden, N. E. (1985) Mean fission neutron spectrum energies for 252Cf and fissile nuclides 233U, 235U, 239Pu and 241Pu, in Proc.
These tables, or their various combinations, could then be entered into the treatment planning computer. This was an identical procedure as previously practiced for radium. Additionally, accuracy of the dose determination at any point was estimated to be within 6% of two standard deviations. The same method was used by Anderson et a/  to construct along & away tables for afterloading seeds with an active length 4 rom; however, such seeds have never been used clinically. Table 8. Neutron Dose Distribution  in cGy JIg" h".
Walker, V. W. (1975) Equipment and Operations for Preparing 252Cf Neutron Sources for Interstitial Cancer Radiotherapy Research, DP-MS-75-9, Savannah River Laboratory, Aiken, South Carolina, CONF-751101--21. 20. Laxson, R. R. (1994) Fabrication of medical implant tubes for interstitial and intracavity applications, Oak Ridge National Laboratory, unpublished manuscript. 21. Laxson, R. R. (1996) Oak Ridge National Laboratory, personal communication. 22. Permar, P. H. (1977) Safety Analysis ofDoubly Encapsulated 252CfMedical Sources (Models ALC, SALC, AT), SRL-76002 Rev.
Californium-252 Isotope for 21st Century Radiotherapy by Jose Feola (auth.), Jacek G. Wierzbicki (eds.)