Calcium-binding proteins in health and disease by Anthony Norman PDF

By Anthony Norman

ISBN-10: 012521040X

ISBN-13: 9780125210409

Calcium-Binding Proteins in wellbeing and fitness and sickness contains the papers ready by way of the invited audio system in addition to some of the loose communications. The contributions are grouped in response to their common subject material, according to the class made by way of the authors, e.g., Extracellular Metabolism: Calcium Homeostasis; Low-Affinity Calcium-Binding Proteins. There might be little question that calcium-binding proteins is a box of clinical exercise so that it will proceed to supply result of nice curiosity to fashionable biology.
This publication is split into 8 sections, the 1st of which, take on extracellular calcium metabolism or calcium homeostasis. the following sections concentrate on issues equivalent to low-affinity calcium-binding proteins; calcium and membranes, channels and delivery (pumps); the function of calcium in complicated metabolic techniques; and gene constitution of calcium-binding proteins and their expression. different chapters hide actual stories on calcium-binding proteins, together with X-ray, crystallography, and NMR; structure-function relationships of calcium-binding proteins and their ambitions; and calcium-binding proteins in wellbeing and fitness and sickness.
This e-book might be of curiosity to practitioners within the fields of biology and medication.

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Extra resources for Calcium-binding proteins in health and disease

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R e c e n t studies suggest t h a2t the 2+ of extracellular Ca involves the interaction with a C a - b i n d i n g protein ( C a receptor) on the surface of the p a r a t h r y o i d cell and t h a t the activation of this receptor is intimately linked to the regulation of P T H 2 + 2+ secretion (1-3). T h e evidence supporting this view is based on m e a s u r e m e n t s of the c o n c e n t r a t i o n of intracellular free C a , [ C a ] . , using 2+ the fluorescent indicator fura-2. These studies reveal that small increases in t h e c o n c e n t r a t i o n of extracellular C a e v o k e rapid a n d t r a n s i e n t 0 I 94- increases in [ C a ^ ] .

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1983). 3 . H i s t o c h e m . C y t o c h e m . 3 1 , 4 2 6 . , and G o r d o n , 3 . (1979). Sci. USA 76, 4 3 5 0 . Proc. Natl. Acad. W a s s e r m a n , R . H . , and F u l l m e r , C . S . (1982). In " C a l c i u m and C e l l F u n c t i o n , Vol. II" (Ed. Y. C h e u n g ) A c a d e m i c P r e s s , I n c . , New York, pp. 175-215. S P E R M I N E E V O K E S2+T H E R A P I D M O B I L I Z A T I O N O F C E L L U L A R C a IN P A R A T H Y R O I D CELLS E. F. N e m e t h A. Scarpa Case W e s t e r n Reserve University Dept.

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Calcium-binding proteins in health and disease by Anthony Norman

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